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mxassasin t1_j6ihy18 wrote

As well as give you a better chance at a longer life, so it balances out.

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Brianprokpo456 t1_j6isntb wrote

No no no. That's not how aging works. OP, please read a basic human physiology book before making such claims.

Aging depends on a lot of factors, yet creating more muscles won't make you age faster. Actually, doing excercise expands your life expectancy.

There is no scientifical correlation between making excercise and dying sooner, unless you take anabolics.

From all the theories that involve aging, the most popular is the cathastropic theory of aging which involves the fact that aging is a product of the accumulation of several errors in a cell and therefore the entire system/apharatus/individual.

While increasing the rate at which certain reactions take place (principally those which are related to DNA replication and cell proliferation), tends to give place to those errors, there exists in the human system a certain limit at which a cell can decide to.

Our cells don't just infinitely divide and increase the number of cells vulnerable to this failure when there is a nutritional superávit, but when there's too many nutrients, they get either redirected to the blood or stored inside.

And as with excercise, that simply is wrong. There is no correlation between one and another, where shows to be proportional. Actually, they are inversely proportional.

OP, the concept you have of "metabolism" is too vague and obscure. You should try learning more about the subject before making a medical claim.

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ShadesOfPoods OP t1_j6iuwzr wrote

I absolutely agree with my lack of understanding of "metabolism". But if you look at it from a broader perspective, don't you think aging is caused by cells in our body trying to maintain itself?

All I'm saying is, building more cells in your body would ultimately cause more "maintanence" to be done (with the same DNA in the cells), which will in turn cause faster accumulation of Catastrophic Aging errors.

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Brianprokpo456 t1_j6iyjre wrote

Mantainance is already covered efficiently by the different systems/apharatus and the respective cells's inner working. It's practically a system with such a low failure probability, that (talking in vague words) isn't primarily responsible for aging process.

Surely the acceleration of certain reactions that tend to cell division, increases the probability of mutations which induce "errors". Yet almost every cell in your body also has a plenty (like 8) mechanisms at DNA level, to prevent such things to happen. And quite a few more at RNA and Protein levels. (E.g: checking if protein is folded properly, then folding it as it should or simply degrading it).

Do they happen from time to time? Yes. But remember we also have the inmmune system, which more specifically the natural immunity one, and more specifically the monocyte-macrophage system, involved in recognizing rare local cells with uncommon markers and fagocitating ("eating them") if recognized.

So, in the end we have a whole lot of barriers that prevent such things to happen. So, phisiologically (aka normal) metabolism isn't much of the problem here.

If you assume cathastropic theory, aging is caused by the accumulation of these errors. But the cause can vary a lot. Most of the time is because of the ambient, this is (people will kill me for saying this), the human could be considered a as a "pseudoinmortal" (yes, as crazy as it sounds) system if it is in the perfect ambient. This means: if the ambient has NO nocive elements, then the human can live as long as it's biology lets him to. Which, to this day, nobody knows, but surely is far more than 80 years average.

Nowadays, we live in an agressive enviroment with multiple factors which accelerate the aging process. One of them is the exposure to certain compounds, which interfere with the normal chemical reactions that occur in our cells (from the ones about cell division, to even other programs). This makes those "errors" accumulate, until it's impossible for the system to sustain itself.

Other factors are exposure to radiation (remember the ozone layer?, what about the contamination resulting from radiactive weaponry?), excessive stress (if the acute stress syndrome is too frequent, a human can enter in a permanent-stress state, which gives place to certain illnesses which compromise the effectivity of certain sistems, thus making aging go faster), genetic diseases (not much to explain here), etc...

So yeah, you are right in that sense. But our metabolism itself, is responsible for such little factors of aging, that basically it can be considered as not correlative to aging.

As you've seen, there are a lot of other factors which are involved more heavily in aging. And more responsible for it.

To clarify, I am not a native english speaker, so sorry if the medical terms are not accurate, but I hope the message is clear enough.

Edit: oh, i forgot about other living systems, for example bacteria, remember antibiotic resistance? That is also correlative to those errors, as parasytic systems also (vaguely speaking) leave a local mess, after they've been erradicated (which can take longer if it resists to a certain point the antibiotic), unless we already have antibodies for them.

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Guardiansvn t1_j6ij7xt wrote

On the contrary, working out reverses the aging process. Working out increases vitality.

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