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pegasBaO23 t1_iv93uem wrote

Depends on how they are conjoined, if they share the same circulatory system and liver, stomach/lungs if the drug is taken that way, then most likely yes, but if they are mostly independent in that way it unlikely

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MrPissedHimself t1_iv97s09 wrote

It's hard to imagine conjoined twins not sharing a blood stream else it'd be a rather simple surgery

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pegasBaO23 t1_iv99jd6 wrote

I phrased it a bit wrong, it's more so how much of the circulatory system they share, and how/where it's shared

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Scott_Abrams t1_ivdc9bl wrote

https://www.mayoclinic.org/diseases-conditions/conjoined-twins/symptoms-causes/syc-20353910#:~:text=Conjoined%20twins%20may%20be%20joined,hearts%20but%20share%20other%20organs.

I think it would depend on three factors: the type of conjoining, the type of drug, and thirdly, the dose but yes, in theory, both people could feel the effect of drugs.

Thoracopagus (being joined in the chest) is the most common type of conjoined twins and they typically have a shared heart and liver. As their circulatory system (heart) and waste disposal system (liver) are connected, it stands to reason that a significant dose that is being metabolized by one twin will also affect the other due to the connected systems though likely at different rates. Something like alcohol for example, taken orally, should in theory, affect both twins but inebriate the ingesting twin more heavily as the alcohol is being absorbed through that twin's mouth and stomach and should reach the ingesting twin's brain faster.

Rachipagus (being connected along the spine) is a rare type of conjoined twin and will likely not result in the other twin being affected by the ingestion of alcohol due to the separation of their circulatory system and GI.

Basically, anyone who shares the same GI and circulatory system should in theory, be affected though the rate and effect of that drug would be different. I don't believe there is any research that studies this in depth so I am only offering my conjecture.

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