Check out Thursday boots.... Not their boots, but they make a genuine leather 'sneaker' shoe. Since it is genuine leather upper, you can clean it with something like saddle soap, and use some leather conditioner, possibly even some wax product to help with waterproofing. The sky is the limit.

I do not own a pair but found them while looking at their boots. I'll eventually buy a pair though. I like that I can clean and condition them like boots. Theoretically they should last a very very long time.