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Rguy315 t1_irekn1v wrote

Reply to comment by smurfettekcmo in A bold effort to cure HIV—using Crispr by Sariel007

I guess that's the billion dollar question and what they're hoping to figure out with human trials.

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eilertokyo t1_irgwwsu wrote

It’s fairly well understood. CRISPR cuts specific sequences of DNA out. If you’re too precise you won’t remove all the HIV. If you’re not precise enough you’ll cut out all kinds of other spots in the DNA and potentially cause problems down the line. A lot of experimental treatments like this wind up with patients developing leukemia or something else down the line. They state 12 weeks but it would be years before they can say this is safe.

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