Submitted by Sariel007 t3_xxyhgb in Futurology
Lou-Saydus t1_irf6a09 wrote
Reply to comment by JuggernautNo6974 in A bold effort to cure HIV—using Crispr by Sariel007
This could be a miracle treatment. Or, unlikely but possible, this could cause every affected cell to have completely junked DNA essentially dooming him to a slow radiation poisoning-like death. Or it could be anything between the two. We don't really have any (ethical) experience in using crispr in humans in vivo and the unintended consequences are unknown. The most likely outcome is that the viral dna is not completely eliminated and this is only a temporary treatment that reduces the need for anti-virals for a time until the virus is able to re-infect previously treated cells.
Emmangt t1_irfp2ci wrote
I feel your predictionabout the efficacy being temporary is very likely to be the right one. Maybe if the treatment works a few weeks they might try to do it every month for x months and then it would increase the probability that every infected cell has been cured.
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