Possible? Yes, with technological advancements.

Expensive? Extremely.

Options like ultra-high velocity kinetic launchers and directed energy weapons deployed in both space and ground could be capable of intercepting high number of vehicles.

As aid, US will not publish any of the technology it manages to keep secret, because in case shit gets real, it can give huge advantage. Not only that, but best way to slow down arms race is to not create need to develop new weapon systems, and appearing seemingly weak is beneficial in this context.