Yes and no.

Places like the Keck Observatory in Hawaii are still immensely productive. Recently it found a new black hole close to earth and clouds on Saturns moon Titan

These discoveries have been in conjunction with James Webb, and we will definitely be relying on space telescopes more in the future than earth based telescopes. This was inevitable with or without satellite interference.

But we definitely cannot say we’ve learned everything there is to learn by looking up at the stars from earths surface.

I can’t speak to the interference that satellites like Starlink would cause. But earth based observatories are still immensely valuable.