Hello u/LucilleandCharlie,

Thanks for the question. NOA (non-obstructive azoospermia) is a common cause of sub-fertility. The causes can vary from genetic to hormone issues, chemical exposure and varicocele. This means the treatment options are best tailored to the underlying cause. Some cases can be treated with medication however not all. Even the best treatment may however only lead to a small amount of sperm production, just enough for IVF.

There are some studies looking into stem cell therapy, but this is not commonplace.

An alternative worth considering is donor sperm which may or may not be a direction you are comfortable with.