Avoid anywhere West of the Susquehanna that isnt State College or Pittsburgh.

People tend to mind their own business for the most part in PA, even in more conservative areas. Ive gone out plenty of times with my same sex partner and never felt unsafe, but I know transphobia is generally much more rampant for the most part.

Pretty much any of the cities in PA should be fine save for maybe Altoona/Johnstown. The Poconos are usually full of tourists and NY/NJ transplants so I doubt there would be any trouble there either.