Allentown-Bethlehem-Easton, Reading; Scranton/Wilkes-Barre (bus only; has its own regional bus system too, so it can spread out a little bit)

Ardmore; Paoli; Exton (suburban Philly first three); Lancaster, Elizabethtown, Middletown, Harrisburg (all by Amtrak; think all are accessible by bus as well through Greyhound and either SEPTA, CAT, or Red Rose)

I know you said New Hope, but there isn't anything closeby other than the SEPTA regional route in Doylestown or the bus there or at Newtown.

In New Jersey with NJ Transit, the closest I see is in Pennington or near NJ 29 & I-295 area. With the latter option, you could just about bicycle there from the river as both sides have a canal towpath on each side and New Hope/Lambertville are just over 10 miles away, one-way.