I ship a ton of stuff and I always check pricing through the 3 big shippers. USPS, UPS, and Fed Ex.

22lbs isn't the only thing we need to know. The size of the box is a huge consideration. Typically USPS is going to be your cheapest bet. Unless you are shipping something very large, then I would go with UPS. FedEx tends to eb the most expensive service for all sizes of shipping in my experience.