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dragonlhama t1_j9fyvz9 wrote

Yes.

Muscle cells have several nuclei.

Hepatocytes (liver cells) have usually one single nucleus, but, occasionally, we observe some of them with two nuclei in normal conditions.

When fighting some kinds of pathogens, usually large ones, such as helminth parasites, the "multinucleated giant cells" are formed, which are kind of a macrophage megazord.

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Foxs-In-A-Trenchcoat t1_j9g7xqt wrote

In other cases, are multinucleated cells usually cancer?

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Ech_01 t1_j9gkjml wrote

Yes. Cells may become multinucleated cells if something goes wrong during the cell division/fusion which is possible when cancerous cells divide way too often unregulatedly.

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Rough_Drop673 t1_j9hb82h wrote

Yes, if the cells morphology is different than the normal cell, and it’s not specific just to the nucleus, can be shape or size as well or behaviour

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