Existing_Thought5767 t1_iu5gzml wrote
Reply to comment by ELI-PGY5 in Does the cerebral spinal fluid of people with Alzheimer's have a notably different pH from 'normal' people's? by wrhollin
It is 100% the right answer. Just because you are checking pH in blood doesn’t mean it suppose to change when you get sick or something. As people in this have said .2 pH is the most change you will see in the human body, anything more than that change you body literally cannot function. Cells would be destroyed very quickly.
ELI-PGY5 t1_iu5i898 wrote
That’s gibberish. pH of blood changes in specific disease states. Checking blood pH is a common, useful pathology test.
As for 0.2 = “cells destroyed very quickly” “body would literally not function” - you’re exaggerating. A drop of 0.2 (7.4 to 7.2) would not even count as a severe acidosis.
So I rate your comment 3.2% the right answer, not 100%.
Daguvry t1_iu5zvmw wrote
Run blood gases all the time working in Respiratory. That's how we monitor correct vent settings and most COPD patients on BIPAP. I can swing blood pH by more than .2 in less than hour with tidal volumes and respiratory rates.
Out of control diabetics can get really low pH values but that's a metabolic issue, not a respiratory issue. I've seen plenty of diabetics under 7.0 pH where the normal pH values are 7.35-7.45
ELI-PGY5 t1_iu7lm1h wrote
Yeah, I was think of a guy I saw recently with DKA, pH 6.9, not crisp but his cells were also not all dead.
gasdocscott t1_iu8ox4x wrote
I've treated patients with pH less than 6.7 (or lower- the gas machine doesn't go lower). Often DKA, which is remarkably responsive to treatment even at those extremes.
Viewing a single comment thread. View all comments