[deleted] t1_iy1p3dl wrote
The only reason i could think for this being true would be that DNA is more accessible during cell division as opposed to being in a typically condensed state that would be inaccessible to Cas9 binding. It seems like something that would be pretty context dependent and depend on the gene.
Do you have a reference for what phenomenon you are talking about?
Waizac123 t1_iy2rkpv wrote
The nuclear envelope is also broken down during mitosis - which would help if CRISPR is unable to normally enter the nucleus.
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