Yes, big cats, such as lions, tigers, and leopards, produce the same allergens as house cats. These allergens are proteins that are found in a cat's skin cells, urine, and saliva, and they can cause allergic reactions in some people.

The most common allergen produced by cats is called Fel d 1, which is found in a cat's skin cells and is transferred to their fur through grooming. Fel d 1 is the main cause of cat allergies in humans and is present in the fur of all cats, regardless of their size or breed.

If you are allergic to cats and are considering adopting a big cat as a pet, it's important to keep in mind that you may still experience allergic reactions to these animals. It's a good idea to consult with an allergist or other medical professional before making the decision to adopt a big cat.