Viewing a single comment thread. View all comments

CardiOMG t1_j2kjnw9 wrote

Reply to comment by scottyboy218 in When pharmaceutical companies develop new prescription drugs, do they test every method of delivery to the human body? For example, injected, orally, topically, rectally, etc? by scottyboy218

The answer is no, they don’t. Those modalities are tested and approved by the FDA individually.

11

IamBatma t1_j2mhmdc wrote

Most drugs have a delivery dependent on molecule type. Most „small molecules“ are delivered orally as they can pass through the intestinal walls and are not denatured whereas big molecules (for example antibodies) would be denatured in the gut and hence rendered useless which means they are generally injected. Another thing to consider is pharma cocinnetics but in the end you will never be able to use a big molecule drug in a pill to be swallowed

5

nothingtoseehere____ t1_j2mad3o wrote

No, the FDA does not run these tests. They'd have to pay for them then, rather than get the company to do them and pay for them.

3

CardiOMG t1_j2mmesf wrote

I meant tested (by the companies) and then approved (by the fda). I know lol.

2