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research_guy17 t1_j4cvxlz wrote

You could attempt "any mouse off the street", but primarily tumor xenograph models are established in SCID mice, bred and cloned for the function. SCID means they are immune deficient, otherwise the immune system of the regular mouse would likely generate antibodies to the injected cells and either reject the attempt to grow the tumor or result in poor health or even death of the "regular" mouse.

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