That’s why I said “related” and not “caused by,” since we don’t know the exact causal mechanism. But beta amyloid PET imaging is used to make Alzheimer’s diagnoses because levels do correspond to severity, for the most part. I work in neurology research.

Edit: also the article you’re referencing really only proved one lab was completely corrupt and shady. There are DOZENS of other b amyloid labs (and subtypes) and quite literally HUNDREDS of preclinical studies whose b amyloid work is supported, which is why clinical trials keep going that direction. Unfortunately they fail. There isn’t some big conspiracy to NOT cure AD. The Science article claiming otherwise was really really sensationalist. But I agree we don’t have a handle on it right now, and other therapeutics are needed.