Pantone colors are one level removed from the RGB representation of those colors which allows the application to adjust the RGB values to best represent the correct shade to compensate for differences in specific computer monitors. To get the most accurate representations the monitor will need to be calibrated using a feedback loop (a camera) that feeds back the color produced for a specific input value to get the closest representable version of each Pantone color.

When fully calibrated a print that uses Pantone should look as nearly as possible like a faithful copy of the image as presented in Photoshop. Colors that are represented in RGB will have some reciprocity errors in the translation to CMYK (or whatever standard the chosen printer uses)