The answer to this is easily google-able. The short answer is you need to keep your wrists up. Your knuckles should be lower than your wrist, and your fingers below that. Adjustable arms rests, adjustable keyboard trays, mouse pads with wrist rests. Whatever it takes to have you comfortably supported in a position where your knuckles are lower than your wrist. Like the way a trained pianist holds their hands up while they play. You'll always see their wrists up in the air, never down low so their fingers need to reach up to the keys. Wrists in the air.