Hmmm, If i may take a guess, execution.

There is a really old game called "Clock tower" which basically uses the same hideandseek mechanics as Alien Isolation. But Clock tower executes it so well that a hunchback with a pair of giant scissors terrifies you. He is slow, you can evade him a lot of times, but everytime he appears it is hard not to panic. While after the 5th death in Alien Isolation you just go meh and load the save file.

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And Dead Space mix them both along with scarcity of resources, you have several on-the-run decisions while the dread and jump scares happens, along with the Necromorphs. Also the bizarre deaths.