Everyone's personal experience will be different on this one I suppose. I had been using Android phones since the Note 2 was a thing and I switched to a 14 Pro back in December. I had no issues transitioning from Android. Yeah there are differences like knowing where to find settings and such, but if you can operate one you can operate the other. They aren't that much different.

You will have to get used to things that just don't exist in the iOS world, such as web based messaging and bluetooth file transfer (unless you use a Mac). That was probably the biggest struggle for me, but as far as using the phone ... it just isn't that much different than using an Andoid phone.