My sister actually moved to Ohio a few years ago - Athens county near the border of West Virginia. Having lived in MA all my life I was blown away by how low the rents were in OH. She rents a 3 bedroom house for about what I pay for my 350 square foot studio an hour west of Boston. I’d like to move out there myself but there isn’t nearly as much in the way of work for my field as there is here in the industrial northeast. You’re literally moving from one of the lowest cost of living regions of the country to one of the highest, so unfortunately your housing will be significantly higher.