William Wyler, best-known for directing glossy romances and melodramas during Hollywood's Golden Age (Roman Holiday, Mrs. Miniver, The Heiress, Ben-Hur) took a sharp detour into horror/thriller territory with 1965's The Collector, set in gritty postwar Britain, and it's fantastic. He went back to lighter territory with his subsequent films (How To Steal A Million, Funny Girl), so The Collector really is the big outlier of the bunch.

Similarly, Michael Powell (A Matter of Life and Death, The Tales of Hoffman, The Red Shoes, The Life and Death of Col. Blimp, etc) with 1960's Peeping Tom - a film acknowledged as a masterpiece of horror and suspense now, but so utterly reviled at the time it more or less entirely killed his previously-respected career. One reviewer even compared Powell to the Marquis de Sade, which seems a bit much.