I think most of Zendaya's fame has come from other things than Spider-Man. She was already known for her music before the MJ role, then MJ made her more known to the general public, and I think things like Dune and especially Euphoria has propelled her. Euphoria is a lead role in a really popular series where her acting has been praised and she's an executive producer on the show too.

Letitia, at least for me personally, I only know her from Black Panther. And until recently, her role in Marvel was pretty small. She was a supporting character in the first movie and was barely in any others. BPWF is her first major starring role, so it may propel her now.

But she also had some controversy for her stance on vaccines in 2020, which has died down, rightfully so. But regardless of public opinion, Studios may not have wanted to work with her during that time because of the controversy. But, I think that will change after her performance in this movie.

At this point, I think it's up to how good of an agent Letitia has. If her agent can get her a big role outside of the MCU, then she may become more popular. I hope she does, she was great in BPWF.