From a science fiction perspective there's Them! (1954) and It Came from Outer Space (1953). There are episodes of the original Twilight Zone and Outer Limits like that too.

If you want something a bit different, take a look at The Flight of the Phoenix (1965). It's about a group of people who are stranded in a desert when their plane goes down. It stars James Stewart.

Then there's films like Lawrence of Arabia (1962), Sahara (1943) and The Treasure of the Sierra Madre (1948) both with Humphrey Bogart, The Lost Patrol (1934) with Karloff in a minor role, The Walking Hills (1949).