From Dusk Til Dawn. Seth Gecko.

The Hunt for Red October. Captain Bart Mancuso and the crew of the Dallas live to hunt down enemy subs and bring them to bay.

Nobody. Hutch Mansell is a wolf. He's also the protagonist.

Heat.

Blade Runner 2049.

First Blood is about a wolf cornered by a pack of angry dogs.

I could probably name one or two rom-coms that fit, but I don't really watch rom-coms, and nothing comes to mind.