Ohiopyle. Moraine. McConnell Mill. Depending on where you live, North Park.

Honestly if you haven't been to Ohiopyle it's definitely worth going. About an hour and ten ish out, you can also check out Falling Water or Yough Lake at the same time.

My husband and I just stayed in Tappan Lake. It’s a little over an hour from Pittsburgh and the cabins are new and right across from the lake. We got the mini lodge because they were running a bogo special that’s going on until the end of February. There isn’t a lot to do there but they have a store with food and drinks and the marina is a mile away with a restaurant and bar.

https://tappanlakesideresort.com/

We also love Deep Creek, Hocking Hills (a little over 3 hours), Cook Forest & Treasure Lake.

Laurel Highlands. Ligonier is a nice little town.

Chautauqua Institution in NY is a really neat old town on a beautiful lake. Only been in the summer so I’m not sure how it is now.

Deep creek Maryland. Hit the casino on the way. It’s roughly at the half way point.

Really good suggestions here for cabin / mountain / wooded getaways and it sounds like that's what you're after. If you looking at other suggestions and want a more urban setting, honestly Cleveland is pretty kick ass for a quick weekend getaway. Art Museum is killer (and it's free!), Cleveland Zoo is pretty great, obviously rock n Roll Hall of Fame. And there are a lot of cool little areas - Tremont is pretty cool, has an amazing "dive" bar with excellent food in the Rowley Inn as well as Prosperity Social Club, a few cool breweries (Phunkenship is a pretty neat spot if you're into wild fermented/sours) and the Westside Market. Could easily make a quick weekend out of a trip to Cleveland.

Oglebay