The research is unique in establishing the most deleterious factor that causes Alzheimer's disease in relation to the others such as lack of exercise, sleep, poor nutrition, and drug use.

The result suggests that social lifestyle determinants are linked to most neurodegeneration risk factors, making them promising targets for preventative clinical action.

It could help with making more informed decisions for policy interventions, especially among the elderly. Social isolation is arguably easier to modify than the other factors