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socokid t1_j8rs5lm wrote

> Up to half of individuals who contract SARS-CoV-2 develop symptoms of long-COVID approximately three months after initial infection. These symptoms are highly variable, and the mechanisms inducing them are yet to be understood.

So, many of the questions people will have about this are simply not going to have an answer yet, unfortunately. I see several for this submission already.

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jonathanrdt t1_j8s328q wrote

At least we are finding significant differences to drive further research and testing. That’s usually how it begins.

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dumnezero t1_j8wigeu wrote

The important part is:

>Based on our results we propose that immune exhaustion perpetuates long-COVID due to the seemingly complete reduction of IFNγ and IL-8, as well as significant decreases in IL-2, IL-4, IL-6, IL-13, and IL-17. Identifying these and other deficiencies will provide clues towards methods to intervene and possibly restore immune function in the context long-COVID. Although functional assays that test the ability of immune cells from individuals with long-COVID to respond to pathogenic stimuli will be required to support this theory.

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altcastle t1_j8xhecr wrote

I got sick for at most a day in Nov 21 and this all hit my suddenly end of Jan 22. They can’t even be sure I had COVID but given how I had sudden LC symptoms that’s what my doctor said was very likely. Always wondered why it came months after like a 1 day mild fever.

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randerton1 t1_j8v4sb5 wrote

State your study here - I don't believe this stat...

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needsexyboots t1_j8y0unr wrote

What do you mean “state your study”? It’s a direct quote from the article the post is about

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randerton1 t1_j8y3gh8 wrote

Whoops - sorry - should have clarified. I meant any additional studies that validate this statement. This statement defies common sense from those of us in the real world who are surrounded by Covid victims of all age groups who have shown no long Covid symptoms 3 months after initial infection.

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needsexyboots t1_j8y54i6 wrote

Honestly in my personal experience, half isn’t that surprising or far off. Of course, I’m not doing a study or anything, but I’d say more than half of the people I know who have had Covid experienced symptoms for months afterward, including myself - I finally have gone a couple weeks without noticing anything and I got Covid in August

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Ok-Training-7587 t1_j8uz1ap wrote

That stat can’t be true. HALF? We’d see it all around us

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opknorrsk t1_j8v31ko wrote

I've seen many people that don't want to believe they have long covid because "it cannot last that long" etc, but have headaches, persistent fatigue etc.

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Ok-Training-7587 t1_j8w2evy wrote

not half though

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2drawnonward5 t1_j8wsqhj wrote

We're talking about long COVID, not chicken pox. You've lived your whole life surrounded by people masking their problems so why would it surprise to know many people are sick?

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Ok-Training-7587 t1_j8wu4n1 wrote

yes, everyone is feeling terrible and they're all hiding it from me

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2drawnonward5 t1_j8wwdv6 wrote

Everyone would be ridiculous. The point is you don't see so you can't know.

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OkGrapefruitOk t1_j8wbf3g wrote

"Up to half" doesn't mean half. It means various studies have found different amounts and the highest was a half.

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sharkman1774 t1_j8y22jk wrote

Here is a link to the study that this study cites about prevalence of long covid

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pete_68 t1_j90211c wrote

It says "up to half". This is kind of a tough number to get a handle on and it depends on how you look at it and what time frame. At this moment, of the people who have had COVID, only 11% currently have long COVID symptoms and an additional 17% have HAD long COVID at some point, so that's 28%. Most people who get long COVID have their symptoms resolve within a year.

But in June of 22, that number was 35% (19% current 16% ever).

So it may be based on a specific time period during a certain outbreak.

But again, the vast majority of long COVID cases resolve within a year.

Source: Kaiser Family Foundation

Edit: I forgot to mention, there's also been some discussion that a large number of long COVID cases go unreported. My own daughter had long COVID and we never reported it. It was mild and it eventually resolved itself, but we never took her to a doctor for it, so it never ended up in the stats, so that might be factored in as well.

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