Viewing a single comment thread. View all comments

Milan__ t1_j9zr6ik wrote

Is it fair to assume that a low carb / low GI diet is a preventable measure against AD?

6

faiththeillustrious OP t1_j9zt8jt wrote

Yes. Less sugar/artificial sugars/insulin spiking foods = less insulin = greatly lowered risk of insulin resistance = lowered risk of CNS insulin dysfunction and neurodegeneration = lower risk of AD. Insulin resistance causing widespread insulin dysfunction which eventually overrides the CNS's defenses and causes CNS insulin malfunction is what causes AD.

12

faiththeillustrious OP t1_j9ztlha wrote

There is a fantastic diagram within the original article of the post depicting how peripheral insulin resistance seen in Type 2 diabetes progressively invades the CNS. (Figure 1)

3

roygbivasaur t1_ja21rug wrote

Do you know if there’s been any Alzheimer’s studies with medications that combat insulin resistance like metformin and GLP-1 agonists (semaglutide and tirzepatide)?

2

Nyxtia t1_ja2quqq wrote

I remember listening to a talk where apparently metaformin was being studied for anti aging potential since it seemed to reduce a range of diseases that occur with increased age like AD and cancers.

2

lost_in_life_34 t1_ja0fyic wrote

Having your foods with carbs also have a high amount of fiber is probably more important than counting carbs

5