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-downtone_ t1_jai7ztp wrote

In my case it was related to low GABA. The primary inhibitory neurotransmitter. Both my father and myself diagnosed bipolar. Both related to low GABA. He then died from ALS, also caused by prolonged low GABA. In both our cases, it's a result of GABA:glutamate ratio. With no inhibition, you have bipolar like symptoms. Just saying.

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smuggles908 t1_jaibz3f wrote

Trauma has also been shown to activate DNA that leads to brain diseases.

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-downtone_ t1_jaid4ib wrote

Yep. My father was a combat wounded vietnam veteran. Took eight rounds and had his leg completely shredded by mortar shrapnel. Seems it can also be passed genetically so there is more to it than currently understood.

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smuggles908 t1_jairng4 wrote

Research has shown that it does pass genetically yea.

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