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zyl0x t1_iu8q7vn wrote

Do you know this for certain with the RA and PsA antibodies, or are you saying in general that we never lose antibodies? Because the latter is not true.

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Bolynn t1_iu8ubp4 wrote

That’s in autoimmune diseases in general. So in RA you’ve got auto-antibodies against antigens that can be found in your joints. So basically there is an inflammatory trigger in your own body that keeps on reinforcing the production of these antibodies. In PsA autoantibodies don’t play a a big role in the formation of arthritis.

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