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1

R-T-O-B t1_ist73ok wrote

"stillbirth can be inherited" That sounds counter intuitive

31

IFuckedYourDadd t1_isth5hg wrote

Do people in these comments not know how genes work? Obviously the ones that aren't stillborn may still carry the genetics to have stillborn babies.

Some women have a stillbirth the first time, then have a successful birth the second time for example.

177

thulesgold t1_isthnfc wrote

How does a risk come from an Uncle or from a cousin when they are not directly related? They may serve as indicators, but the risk doesn't "come" from them. Bad title.

16

slowkums t1_istitm3 wrote

If you think about it, it would be kinda hard to pass down through the mother's line...

6

socio-pathetic t1_istm9eh wrote

Yes, my father was stillborn and so was I. My poor son, I hope he hasn’t inherited it from me!

−10

--his_dudeness-- t1_istmpq3 wrote

Can someone please comment on the quality of the research and not the title?

18

m674 t1_istodft wrote

She doesn't, she inherits it from her father, the same person the brother inherited it from. However, if the mother has a child, the "gene" for stillbirth for that child will come from the infant's father, not the mother. However, if her brother has a child, his child will have his stillbirth "gene".

If the woman noticed her husband's brother (brother in law) has multiple stillbirth infants, this would be more concerning than if she noticed the same thing with her brother.

33

[deleted] t1_istrl25 wrote

>That risk preferentially comes from the mother’s or father’s male relatives—their brothers, fathers, grandfathers, uncles, or male cousins.

Nature clearly doesn't want women to have their brother's, father's, grandfather's, uncles, or cousin's babies.

−7

scooterjay2013 t1_istxs5x wrote

At the risk of making light of a serious situation… If your parents didn’t have children, chances are you will not either.

8

catchallt3rm t1_isuc7os wrote

How can a receptor be associated with "more siblings"? Unless this
genetic variant was more commonplace among those from large
families/the middle class? Middle class women in England from over a
century ago were treated like broodmares - their downwardly mobile
children were continually replacing the lower classes. That's basically a
recipe for decreased genetic variability and more frequent 'variants'
like these.

2

Doingmybest2019 t1_isukpuk wrote

Does this mean it’s a y-linked chromosome disorder?

2

Chronotaru t1_isuou9c wrote

Not entirely surprising. Although not directly relevant, the Y chromosome is littered with genetic trash. The allowable mutation range for females of any species to successfully carry out and survive the birth of healthy offspring is far more restricted than with men. Not surprised if men can be a carrier for dodgy X chromosomes too.

10

xlews_ther1nx t1_isuqu9v wrote

As a husband of a wife who has had multiple miscarriages (and insurance won't cover test fir several more), I'm glad to hear this so maybe my wife will stop blaming herself all the time.

93

d4dog t1_isuyayj wrote

This isn't science, this is the result of lack of science in basic education. I suspect with most ot the research was rooted in the Old Testament.

−6

BoredMamajamma t1_isv4m24 wrote

The risk for stillbirth can be inherited.

It’s saying that there is a genetic risk for stillbirth which can be inherited by the mother or father but is passed along male family members (fathers —> children).

10

urkish t1_isvfqu7 wrote

> the Y chromosome is littered with genetic trash. The allowable mutation range for females of any species to successfully carry out and survive the birth of healthy offspring is far more restricted than with men.

Got any more I can read on this, first I'm hearing it?

3

Lok_Die t1_isvjhya wrote

It's old science. It is mostly out of date and incorrect. What is correct about it is if you take genetic trash and change the words to duplicated genes, then it would be correct.

Men carry a Y chromosome that is more or less intact from their fathers so on and so forth into history, as this particular chromosome does not recombine with the X chromosome. Which in a weird way means the Y chromosome reproduces itself A-sexually, it is more of a clone of the one boys share with their fathers. Also it seems that according to this paper the Y chromosome has been subjected to intense selection forces that have Whittled it down to the size that it currently is. In fact it is mentioned in this article that the Y chromosome has been very stable for a very long time. Although it does mention that when the Y chromosome doesn't have enough duplicates of certain genes it can result in heavy fertility issues in men.

15

nochancecat t1_isw2blx wrote

Wait, so my mom had a stillborn, 3rd child. My brother never had kids, but he was at a higher link of passing this on than me? Or do I have the same risk that I got from my father? I've never had a pregnancy issue. Do my kids have a higher risk or just my son?

1

vicky1212123 t1_iswm73d wrote

This makes sense! My mom was stillborn so I guess it makes sense that I would be too. I wonder if my future children will be stillborn like their mama

1

asdaaaaaaaa t1_iswmyfp wrote

People highly overestimate the average age of people on reddit I'd imagine (and how many of them are actual people). I wouldn't be surprised if the average age was around 14 or so, like a lot of other online games/groups. Looking at certain popular comments, it's pretty clear sometimes many people here have never held a more career-oriented job, or done a decent chunk of "normal adult things".

3

TheFunfighter t1_iswvmqz wrote

So does this mean the male genetic contribution to the baby is at fault, or is it a problem coming from the carrying female, that is inherited from her own father? Who has the genes that are at work in the stillbirth? The father or mother of a child? Read the title and went through the article, but still can't really comprehend it. I only know the gene is passed on through men. But in who does it have to end up for things to go wrong?

1

Jiffyman11 t1_isxuuc7 wrote

Some guys just have bad seed.

1