Meatrition OP t1_itfa2th wrote on October 23, 2022 at 5:21 AM

Result The prevalence of Pre-DM was 9.77%.The median TG/HDL-C ratio was 0.671 (interquartile range, 0.468–1.010). After adjusting covariates, the results showed that TG/HDL-C ratio was positively associated with Pre-DM ((OR = 1.185, 95%CI 1.145–1.226). In addition, the TG/HDL-C ratio level has a non-linear relationship with the incidence of Pre-DM, in which the inflection point was 1.617. The effect sizes (OR) on the left and right sides of the inflection point were 1.312 (95%CI 1.242–1.386) and 0.980 (95%CI 0.898–1.070), respectively. And the sensitive analysis demonstrated the robustness of the results. Subgroup analysis showed a stronger association between TG/HDL-C ratio and Pre-DM in females and the population with 30 years < age < 40 years, 18.5 kg/m2 < body mass index < 24 kg/m2, and ALT < 40U/L. Conclusion This study demonstrates a positive and non-linear relationship between TG/HDL-C ratio and Pre-DM in Chinese non-obese people with a normal range of low-density lipoprotein cholesterol. TG/HDL-C ratio is strongly related to Pre-DM when TG/HDL-C ratio is less than 1.617. It makes sense to reduce the TG/HDL-C ratio level below the inflection point from a treatment perspective.

SerialStateLineXer t1_itlkwxh wrote on October 24, 2022 at 3:27 PM

These seemed like extremely low ratios. At first I thought Chinese people were just really healthy, but then I realized that because cholesterol and triglycerides have different molar weights, the ratio is different depending on whether HDL and TG are expressed in mmol/L or mg/dL. You need to multiply by about 2.2 to convert mmol/L ratios to mg/dL ratios (the kind you typically get in the US).