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IamreallynotaNPC t1_iv6jlsp wrote

Reply to comment by DucksNQuackers in BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE. - Biological Psychiatry by chilladipa

If your body doesn't have a proper amount of the materials required to create serotonin will the body limit its release? If so that would be a symptom, but if the body has all it needs and still didn't release much then it would be the cause. Then I wonder how do you figure that out even...

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DucksNQuackers t1_iv6kp6j wrote

To further complicate things- does the body have the proper amount of materials, under the correct conditions, in the right location? Then, what if anything else is going on with depression in addition to the serotonin piece?

And so the rabbit hole goes. Love this stuff

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IamreallynotaNPC t1_iv6l5c7 wrote

Serotonin cannot cross the blood brain barrier either, so what is made in the body is used there, and what's made in the brain is used only there, which adds more pieces. It is good that we have some confirmation on one part though.

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