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BandComprehensive467 OP t1_iy2ze7g wrote

Reply to comment by Balthasar_Loscha in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467

interestingly a whole food plant-based diet can easily provide the same amount of salicylic acid as low dose asprin and will provide increased arginine levels.

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Balthasar_Loscha t1_iy4nhf5 wrote

Any information on salicylic acid amounts in plants? They are very very low, iirc. Arginine is effective as a NO donor if it is taken apart from meals. Animal-based, restaurant-type of diet has the best precedence worldwide, and plant-based diets, 3rd World-diets, unfortunately the worst :(

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BandComprehensive467 OP t1_iy51nxo wrote

Yeah salicylic acid is very high in some plants, cumin I believe has the highest at ~1% by weight if I remember correctly. It was observed that salicylic acid in plant based dieters was potentially higher than those taking low dose aspirin and typically much higher than other subjects. https://pubmed.ncbi.nlm.nih.gov/11429429/

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So higher protein diets will have higher amounts of arginine, however, it is the ratio of amino acid that counts most for what is being absorbed in addition to other factors such as blood lipids and what not. Plant based foods have higher ratios but not total amount of several amino acids, arginine being one of those amino acids. This leads to plant based dieters having higher levels of arginine. It is the BCAA that are in a much higher ratio in meat.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863390/

"Vegan children had lower protein intake calculated as a percentage of daily energy intake (13.5% compared to 16.4% in omnivores) and showed lower levels of circulating leucine/isoleucine, phenylalanine, valine/betaine, and aspartate and higher levels of alanine, arginine, and glycine."

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Balthasar_Loscha t1_iy5nsv7 wrote

>It was observed that salicylic acid in plant based dieters was potentially higher than those taking low dose aspirin and typically much higher than other subjects.

No, circulating SA is a hundred times lower in vegetarians and non-vegetarians compared to consumers of low dose aspirin.

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Balthasar_Loscha t1_iy5fdjn wrote

>Yeah salicylic acid is very high in some plants, cumin I believe has the highest at ~1% by weight if I remember correctly.

The intake of SA in a regular diet, even with a high amount of plant intake, is neglible. Rare outliers like the alleged cumin should be ignored.

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BandComprehensive467 OP t1_iy5j6p5 wrote

Why ignore them if you think it is beneficial... anyway there's some in all plants and it adds up to be not neglible

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Balthasar_Loscha t1_iy5jyy2 wrote

"Results: Salicylic acid was detected in every serum sample analysed. Higher serum concentrations of salicylic acid were found in vegetarians than non-vegetarians: median concentrations of 0.11 (range, 0.04-2.47) micromol/litre and 0.07 (range, 0.02-0.20) micromol/litre, respectively; the median of the difference was 0.05 micromol/litre (95% confidence interval for difference, 0.03 to 0.08; p < 0.0001). The median serum concentration of salicylic acid in patients taking aspirin (75 mg daily) was 10.03 (range, 0.23-25.40) micromol/litre, which was significantly higher than that found in non-vegetarians and vegetarians."

The contribution of diet to concentrations of SA is neglible, and not useable as a replacement for low dose Aspirin

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