Gastronomicus t1_j2fjdhd wrote
Reply to comment by Weaselpanties in Intensity of psychedelic experiences after taking psilocybin does not depend on body mass index, study suggests by nikan69
>While body weight-adjusted dosing is widely used, this imposes a practical and financial strain on the scalability of psychedelic therapy
That just doesn't make sense. I don't see how they can claim that since the effect does not scale with BMI this somehow mitigates the need to dose according to body mass, for which dosage almost certainly scales.
Weaselpanties t1_j2fl9hv wrote
That isn't what it says they're claiming at all. "this imposes a practical and financial strain on the scalability" is just a way of saying that it gets more expensive for bigger people.
They did the study in part to determine if it's actually necessary to scale up for people whose additional size is mostly fat, or if they can take the same (smaller, cheaper) dose as someone who is their height but has less body fat.
hazpat t1_j2fr2zi wrote
It most certainly does not scale with body mass. This isn't the first time a paper published this common knowledge among users.
https://journals.sagepub.com/doi/full/10.1177/0269881121991822
Gastronomicus t1_j2fwumz wrote
I'm specifically referring to the OP paper where they make this claim based on BMI, not body mass.
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