carbonqubit t1_j4xzyjn wrote on January 19, 2023 at 1:17 AM

Reply to comment by jojomaniacal in "Origami" DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells. by filosoful

It looks like they used UV light with a wavelength of 310 nm to directly cross-link thymidine bases. Nearby pyrimidines are converted to cyclobutane pyrimidine dimers, which then pair with the free thyminde bases to build the cone shaped nanostructures.

jojomaniacal t1_j4y8lfm wrote on January 19, 2023 at 2:20 AM

Oh wow that's much more targeted and sophisticated than I was thinking. Origami really fits for what they did there.