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Moont1de t1_j50el9y wrote

Reply to comment by smallgovisbest in The Benefits of Taking Vitamin D Might Depend on Your Weight | A reanalysis of a large trial found overweight and obese people might metabolize vitamin D supplements differently, leading to lower circulating levels by Hrmbee

The issue with increasing the dose is that you're increasing the amount that gets stored in fat, which can lead to hypervitaminosis when the stored vitamin D inevitably gets released. I don't think such a study is ethical.

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