I have bipolar it's not fun. But I've never had issues with psychedelics. I do prefer mushrooms though. I've had a lot of personal break throughs and doing a large dose holds me over well for about two months. I know some of the worries with people who are mentally ill using psychedelics but nothing else works like this does. I've tried a ton of meds and none of em do much for me. I'd rather eat a natural mushroom every few months than to swallow a few pills everyday. I'm glad they are finally digging into the benefits of it.