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AsuhoChinami t1_j1s2vk0 wrote

Reply to comment by pre-DrChad in Sam Altman Confirms GPT 4 release in 2023 by Neurogence

How common is AI in drug discovery now? Last I read up on it was 2020 maybe. Back then, it was common among new start-ups, but nobody else. Hell if I know why. New thing bad, I guess. How much time does it shave off the 12-15 year creation pipeline?

And I had no idea silico models were being used. Is that a very recent development or something? When I last looked into this in 2019/2020 it was still more theoretical.

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pre-DrChad t1_j1s4v22 wrote

Look up Insilico medicine, I believe they are the company that uses AI the most for drug discovery. They already have a drug for idiopathic pulmonary fibrosis that was developed completely by AI

And organ on a chip models are already being used. Full scale in silico models not yet, but like I said maybe proto AGI enables that.

Development shortens the drug development pipeline by like 90%+, and in silico models could shorten trial process by years. Go straight to phase 3 human trials skip the previous steps etc

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AsuhoChinami t1_j1sd254 wrote

90 percent? Do you mean that AI and organ-on-a-chip shorten the whole process has shortened the process from 12-15 years down to 1-1.5?

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pre-DrChad t1_j1sfgqy wrote

No 90% is specifically for drug development only. I don’t know the exact number 90% is just an estimate. But I’ve read AI speeds up drug discovery a ton.

And with full in silico models instead of clinical trials taking 10+ years, it will take 2-3 years instead. Pre clinical testing on the in silico model should take under a year, and then the phase 3 trial on humans should take 1-2 years.

So overall the entire process from developing a drug to getting it on the market could go from 15 years to under 5 years.

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