I think it's valid to bring up.

I'm all for the legalization but think education is also important.

I also understand those that are pro-legalization have been arguing against the "harmful effects" for so long that some feel there aren't any harmful effects. It's nowhere near the level that's been spewed to us for decades, but there is potential harm in smoking or undesired effects, and anyone that intentionally (or unintentionally) intoxicates another animal or non-consenting human I would consider cruel behavior.