Yogs_Zach t1_ixvw4jo wrote on November 26, 2022 at 8:03 PM

Reply to comment by honey_rainbow in Brain cancer vaccine succeeds at prolonging survival in Phase 3 trial by Sorin61

I wouldn't say groundbreaking, but it's promising. It increases survival rate from 5% to something like 13% past 5 years. I think groundbreaking would be something like 20%, 30% or 40% or more

virtuesdeparture t1_ixvzm7d wrote on November 26, 2022 at 8:27 PM

My dad died of GBM two years ago. Dcvax is nearly tripling five year survival rates after 20+ years of absolutely no progress in treatment or survival times. 13% might not sound like much, but GBM is a death sentence.

beehive000 t1_ixxf1s1 wrote on November 27, 2022 at 3:12 AM

Agreed. My dad passed from GBM in July. I’m so sorry for your loss.

Yogs_Zach t1_ixxnk2x wrote on November 27, 2022 at 4:27 AM

I'm sorry to hear that, and I didn't mean any disrespect with my comment.

I just think it would be prudent to temper expectations with this very deadly disease. Tripling the survival rate is wonderful, but from a statistical point of view the odds of survival increase by just 8% at the 5 year mark. Everything helps of course.

One of my biggest concerns is how expensive this treatment will cost and what insurance may cover it. From the article, it seems to be a very involved, customized, process. Many insurances may not elect to cover it if their cost/benefit analysis formulas show it's not mathematically viable for them.