Viewing a single comment thread. View all comments

elijah112358 t1_j0yttnk wrote

Reply to comment by jayhasbigvballs in Molecule that mimics insulin opens new doors for a diabetes pill by rchaudhary

many people are also able to control T2DM with only basal insulin (i.e. long acting insulin that isn’t bolused at meals)

5

jayhasbigvballs t1_j0zfb7f wrote

Sure. But type two diabetes is progressive and almost all those patients will eventually fail because of the nature of their disease. What will make this drug useful is if it was the only thing required, aka a short acting insulin mimetic, which will actually regulate blood sugar in an impressive way. Most type 2s on long acting are also on other oral antidiabetic medications because long acting just doesn’t really lower blood sugar a whole bunch.

Source: I’m a type 1 diabetic, did my PhD in metabolic disease, and worked in research for a large pharmaceutical company in their diabetes portfolio.

6