anormalgeek t1_j0yvea5 wrote on December 20, 2022 at 1:04 PM

Reply to comment by anonprogtada in Molecule that mimics insulin opens new doors for a diabetes pill by rchaudhary

Again, flat out untrue. Until the isolation of insulin by Banting and Best, the best you could do was extend life. Cutting carbs alone would give you a few months or a couple of years if your "honeymoon period" lasted longer. Because even fat/protein intake affects blood glucose (to a lesser extent than carbs), many people also followed the "starvation diet", which extended life longer by consuming the absolute bare minimum of calories. It always resulted in death though.

Yes, as I clearly implied, type 2 prevalence has increased a lot due to lifestyle but it has always been more prevalent than type 1. Another major contributing factor is age and people are living longer.

anonprogtada t1_j102adx wrote on December 20, 2022 at 6:10 PM

Seriously? Here's some FaCts:

Type 2 diabetes accounts for approximately 90% to 95% of all diagnosed cases of diabetes; type 1 diabetes accounts for approximately 5-10%

Source: https://www.cdc.gov/diabetes/basics/quick-facts.html

And type 2 diabetes can be put into remission at any stage of the disease, or do you think there is only one path: ever increasing insulin shots, amputation and death?

anormalgeek t1_j10kfhj wrote on December 20, 2022 at 8:06 PM

Again, none of that in any way contradicts what I said earlier.

To quote you directly:

>Diabetes used to be...almost exclusively T1.

I'm talking about that part. Type 2 has ALWAYS been the more prevalent type. Always.

And no, it absolutely cannot be put into remission for all patients. There are some people with completely healthy diets, weights, and exercise regimens that still develop the disease. They are absolutely the minority. I am not disputing that. But you're flat out wrong to claim that doesn't happen. Or that type 1 used to be more prevalent than type 2. Or that people could survive long term with type 1 with lifestyle changes alone before insulin was available. Those are all 100% incorrect statements that you've made.