I don't like how so many anime fans treat source material as sacred. If you want to see the most faithful version of "Trigun" possible, just read the manga.

This is clearly not a faithful retelling. It is using the characters, setting, and themes to tell a unique story. A "remix", effectively. Isn't that way more interesting than just a straight-up panel-to-screen conversion? Doesn't this give us the opportunity to be surprised, or to explore new ideas?