As someone who is insulin resistant and wears a continuous glucose monitor, even low GI foods raise blood glucose, and therefore insulin.

The only food that doesn't raise insulin levels is fat (and maybe alcohol).

Every carbohydrate gets converted into sugar (glucose), as far as our cells are concerned.

Here's my take: your hormones are supposed to be in some form of balance. With modern diet and modern lifestyle, our insulin levels are too high for too much of the day. When you become insulin resistant, your blood insulin levels remain higher for longer.

High insulin levels on their own are damaging to tissues.

Intermittent fasting allows time for insulin levels to come down to safer levels. Eating 6 small means throughout the day, or snacking between meals and late at night, keeps insulin levels too high for too long.

Keys was a terrible scientist that sent us on the wrong trajectory in America, and across the globe. He maligned saturated fat, in part by showing that rabbits fed saturated fat would get heart disease - rabbits! How much meat is in a rabbit's natural diet?

The Greeks he studied were also very Orthodox Catholics, who regularly fasted. They fasted multiple times a month. That is a huge confounding variable that he chose to ignore.

Around the time that Keys argued red meat was killing Americans, other scientists were arguing that it was actually sugar and cigarettes causing heart disease. 70 years later, after a long low saturated fat period, look where we are today.

Ultimately I think radiant floor heating is the most comfortable type of heating you can have. No cold spots, no blowing wind from forced air, humidity remains higher, dust is lower, there is even vertical temp distribution from floor to ceiling.

It just has to be designed correctly with the insulation of the house taken into consideration.

Use water-pipe underfloor heating. Set the boiler or manifold temp to something like 75 degrees, and have it constantly circulate the water.

Control house temp by opening some windows.

Cells don't need Insulin to uptake ketones. The brain can readily burn ketones when they are available.

But then you have all this tall grass that just grows and grows and grows. If only there were some autonomous..... animals that could cut the grass, keep it short, and fertilize it all at the same time....

This one guy in Arizona is doing a pretty good job for his neighborhood. Everyone could do a little something themselves and it would make a big difference

https://youtu.be/KcAMXm9zITg

People who need to escape.... Escape via video games.

If it weren't video games it would be alcohol, over-working, shopping, reading, or a thousand other ways people choose to disconnect with whatever is happening in their life.

Look up the story of Pablo Kelly. 8 years ago he was diagnosed with stage 4 glioblastoma - and given a terminal diagnosis with 6-9 months to live.

He refused the Standard of Care, and started a therapeutic ketogenic diet. Today he is still alive and well. That is unheard of.

As far as cancer mortality being solved - the question is "how many people who died of cancer attempted a therapeutic ketogenic diet after diagnosis?". The answer is "close to zero".

It's a practically unheard of treatment outside of a small sliver of the population.

The genetic mutation theory of cancer doesn't make sense. Why were people relatively free of cancer until just the past few decades. And since then cancer has absolutely exploded (as has obesity and type 2 diabetes - and the thing they share in common is their impact on/from metabolism)

The two primary fuels, from what I've learned, are glucose and glutamate. You can lower glucose significantly with low carb diets and fasting (I can get my glucose down to the high 30s on a 5 day fast, and feel fine doing it. I get orthostatic hypotension on a fast that long, but it's not a big deal).

And the drug DON can lower or block glutamate.

These aren't things you have to do forever, either - just long enough to starve to death the cancer cells.

Correct me if I'm wrong, but no cancer cells use ketones for energy:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235292/#:~:text=Previous%20studies%20indicate%20that%20unlike,viability%20of%20cultured%20tumor%20cells.

Brown adipose tissue is a type of fat that burns fat to generate body heat.

By raising the room temperature by about 12f, rats burned 16-25% less energy than rats kept at the lower temp.

But 12f is the difference between 60 degrees and 72 degrees, and I think we can all argue that 60 degrees is a pretty miserable temp.

To critique the point of the study, people aren't fat because their room is too warm. Look at people in Thailand, India, Vietnam. It's hot as balls over there, and many don't have A/C - and yet those are typically rather lean countries.

On the flip side, NASA astronaut Ray Cronise lost 80 pounds in part through sleeping in shirt and shorts with the window open all year long.

That's actually a good idea.

Except I don't know how common outlet timers are.

Any mention of cow farms as significant emitters via this technology?

LDL cholesterol is frequently believed to be the "bad" cholesterol, and is also the cholesterol that is affected by saturated fat consumption.

Anywhere from 50-75% of people who have heart attacks have normal cholesterol levels, including LDL cholesterol.

So how good of a predictor of heart disease is LDL, and why have we put so much emphasis on lowering LDL when it seems to have little bearing on our heart disease risk?

My triglycerides were at one point 1,200 (whatever the unit is). I have lowered that by 80% through low carb, high fat diets and fasting.

Carb intake has had a far greater impact on my cholesterol ratios than protein and fat does - and yet the advice is to always avoid fats - especially saturated fat.

Increasing your body's ketone levels [helps avoid] the turning-on of new-fat-making hormones, and also helps avoid the condition of insulin resistance.

The soybean oil industry acknowledges that soybean oil causes obesity - and they made a genetically modified soybean oil that causes less obesity than regular soybean oil.

https://www.genengnews.com/news/gmo-sourced-soybean-oil-causes-less-obesity-than-conventional-oil/#:~:text=Long%2Dterm%20tests%20in%20mice,of%20diabetes%20or%20fatty%20liver.

Conversely, full fat dairy products are more protective against obesity when compared to low fat or fat free dairy products

https://www.hsph.harvard.edu/news/hsph-in-the-news/full-fat-dairy-may-reduce-obesity-risk/#:~:text=Contrary%20to%20current%20popular%20wisdom,HSPH)%20nutrition%20expert%20Walter%20Willett.