BorneFree
BorneFree t1_iw47e0v wrote
Reply to comment by Ph0ton in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1
This is interesting I’m actually not well versed in cell cycle arrest in CRISPR editing.
However, regardless of advancements in CRISPR, I don’t think genetically engineered primates will ever become a mainstay of research - the time and expense of generating these animals is exuberant. I have a friend at NIH who occasionally works with primates and the amount of money invested in their primate center is absolutely absurd.
From the time the first embryo is edited, to the F1 generation alone is what, 4-5 years!? It’s just not feasible imo
BorneFree t1_iw33ajn wrote
Reply to comment by Cersad in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1
Take a look at Guoping Feng’s Shank3 macaque KO paper
The off target effects make Crispr primates incredibly expensive to make, and an overall inefficient experiment
BorneFree t1_j9z67bu wrote
Reply to comment by [deleted] in Those idiot in NJ will surely fall for our lies if we make claims with no evidence and pretend to care about the whales like they do! by New_Stats
When carbon emissions continue to cause the earth to warm and LBI is submerged by increasing water levels you won't have that issue!