ChemicalBliss

ChemicalBliss t1_iw3s79v wrote

Reply to comment by turquoise_amethyst in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1

If it’s recessive, they can breed 2 mice that are heterozygous for the mutation and screen the pups for having 2 copies of the mutation.

Edit: if it’s dominant they can use a conditional system where the gene only gets turned on in the presence of a drug (such as tetracycline), or the gene is turned on in a tissue specific manner.

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